Code and scripts for research papers

📃 A repository of repositories containing code and scripts used in research articles, papers and preprints

View as a web page or Github repository.

2025

Genomic investigation of ESBL-producing Escherichia coli reveals likely transmission within and between One Health sectors in Jakarta, Indonesia

Nelly Puspandari, Rahadian Pratama, Richard N. Goodman, Imron Suandy, S Sunarno, Efadeswarni, Tati Febriana, Dwi Febriyana, S. Sunarno, Desrina Sitompul, Asih Hartanti, Ageng Wiyatno, Shannon Quek, Simon Wagstaff, Adam P. Roberts and Thomas R.D. Weaver Research Square (preprint)

Repository of code for paper

• Figure 2 - Geospatial distribution of STs across Jakarta
• Figure 4 - Geospatial mapping of waterways Jakarta Indonesia
• Figure 3A - ANI/SNP matrix for specific STs
• Figure 3B - Geospatial plotting ANI strain distance

Shotgun metagenomic analysis of the oral microbiomes of children with noma reveals a novel disease-associated organism

Michael Olaleye, Angus M O’Ferrall, Richard N. Goodman, Deogracia W Kabila, Miriam Peters, Gregoire Falq, Joseph Samuel, Donal Doyle, Diana Gomez, Gbemisola Oloruntuyi, Shafiu Isah, Adeniyi S Adetunji, Elise N. Farley, Nicholas J Evans, Mark Sherlock, Adam P. Roberts, Mohana Amirtharajah, Stuart Ainsworth bioRxiv (preprint) 2025.06.24.661267; doi: https://doi.org/10.1101/2025.06.24.661267

Repository of code for paper

• Table 1A, Figures 1B, 2 and 3, Figures S2-S4 - Noma vs healthy dataset analysis
• Table 1B, Figure 1A, Figure S1 - Within Noma dataset analysis
• Within healthy dataset analysis

Genomic comparison of highly related pairs of E. coli and K. pneumoniae isolated from faeces and blood of the same neonatal patients hospitalised with fever in Dar es Salaam, Tanzania

Richard N. Goodman, Sabrina J. Moyo, Ilinca Memelis, Aakash Khanijau, Joel Manyahi, Upendo O. Kibwana, Said Aboud, Bjørn Blomberg, Nina Langeland, Adam P. Roberts. bioRxiv (preprint) 2025.04.28.650962; doi: https://doi.org/10.1101/2025.04.28.650962

Repository of code for paper

• Figure 1 - ANI and SNP distance matrices
• Figure 2 - core genome phylogenetic tree
• Figure 3 - variant calling heatmaps with breseq
• Figure 4 - circular whole genome comparisons
• Figure 5 - analysing virulence factor determinants

2024

Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales

Graf, F.E., Goodman, R.N., Gallichan, S. et al. Nature Communications 15, 9019 (2024). https://doi.org/10.1038/s41467-024-53391-2

Repository of code for paper

• Figure 4 - Co-occurence analysis of AMR genes